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There are three bio-identical estrogens:

  • Estrone (E-1)
  • Estradiol (E-2)
  • Estriol (E-3)

These three chemicals make up human estrogen. The estrogen that has the most volume in the body is estriol (60-80% of circulating estrogens), followed by estradiol and estrone (10-20% each). Estriol is thought to be the weakest acting hormone but provides a natural hormonal balance in the body, whereas estradiol and estrone are thought to be the more potent estrogens. The female body produces large amounts of estriol during pregnancy and has protective properties against such things as estrogen-related cancers. Estradiol is the estrogen that can relieve vasomotor symptoms the best. Estrone is the primary estrogen found in post-menopausal women. It stores itself in the body fat and has more known cancer properties.

What are the functions of estrogens?

  • Promote proliferation and growth of specific cells in the body.
  • Responsible for the development of most secondary sexual characteristics of the female.
  • Responsible for healthy growth and development of female sex organs.
  • Provide maintenance of anti-aging mechanisms.
  • Protect against bone loss (but does not assist in the formation of new bone), heart disease, and other aging dilemmas.

What can bio-identical estrogens be used for? 

  • Symptoms of perimenopause and menopause.
  • Natural and surgical menopause.
  • Primary ovarian failure.
  • Infertility
  • Osteoporosis
  • PMS